- Ned Stark. The former head of House Stark may be based on Richard of York and Richard III amongst others.
- Catelyn Stark. Catelyn Stark may draw some traits from Cecily Neville, wife of Richard of York.
- Robb Stark. Robb Stark may be partially inspired by a young Edward IV.
- Sansa Stark. Sansa may be partially inspired by Elizabeth of York.
- Arya Stark
- Bran Stark
- Rickon Stark
- Tywin Lannister
- Cersei Lannister. Cersei Lannister may be inspired by Elizabeth Woodville, the controversial commoner who married Edward IV, as well as Margaret of Anjou.
- Jaime Lannister
- Tyrion Lannister.
- Daenerys Targaryen. George RR Martin may have based some aspects of Daenerys Targaryen on Henry VII.
- Catelyn Stark (nee Tully). Catelyn Stark, wife of Ned Stark, may be based on Cecily Neville.
- Edmure Tully
- Lord Walder Frey. Walder Frey may be based on two players in the Wars of the Roses: Cecily Neville’s father, Ralph Neville, and Thomas Stanley, the opportunistic lord who betrayed Richard III at Bosworth.